Hemostasis Reference Laboratory

Factor II (Prothrombin) Activity

• Transaction Code: 3210-10
• CPT Code (Suggested): 85210

A one-stage extrinsic system clotting assay is used to measure the circulating factor II (prothrombin) level. Clotting times of dilutions of patient plasma are compared to dilutions of a plasma pool from normal donors, when added to deficient plasma. Low values can be caused by hereditary or acquired factor II deficiency, factor II inhibitor, warfarin therapy, disseminated intravascular coagulation (DIC), or liver disease.

• Sample Required: 0.5 ml frozen plasma x4 or (2) 3.2% sodium citrated tubes, 5 ml each.
• See Sample Requirements when ordered with other tests.
• Normal Range: 86-137% effective 11/1/11
• Analytic Time:Performed weekly, available STAT