Platelet Immunology Laboratory

Platelet Autoantibody Test

• Test Code: 3640-00
• CPT Codes: (86022/86023)x2, 83912

Idiopathic Thrombocytopenic Purpura (ITP) is a diagnosis associated with elevated platelet associated IgG, IgM or both. Positive autoantibody test results are indicative of autoimmune destruction. Positive indirect antibody test results, using patient's plasma against normal random platelets, may indicate ITP depending upon the patient's transfusion or pregnancy history. In approximately 85% of patients with ITP the presence of an autoantibody can be detected.

Patients who require autoantibody testing must be platelet transfusion independent for approximately 5 days to ensure that the platelets being tested are the patient's own platelets and not circulating donor platelets.

• Tests Performed: Flow Cytometry
• Test Types: Direct and Indirect
• Samples Required: One 5cc citrate tube (blue top) and EDTA (lavender top) as below:

• Analytic Time: 1 Day
• Send whole blood, room temperature
• Refer to Ordering Information page for submission and transporting requirements