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Fu X, Kassim SY, Parks WC, Heinecke JW: Hypochlorous acid oxigenates the cysteine switch domain of pro-matrilysin (MMP-7): A mechanism for matrix metalloproteinase activation and atherosclerotic plaque rupture by myeloperoxidase. J Biol Chem 276(44):41279-41287, 2001.

Fu X, Mueller DM, Heinecke JW: Generation of intramolecular and intermolecular sulfenamides, sulfinamide, and sulfinamide by hypochlorous acid: A potential pathway for oxidative cross-linking of low-density lipoprotein by myeloperoxidase. Biochemistry 41(4):1293-1301, 2002.

Fu X, Kassim SY, Parks WC, Heinecke JW: Hypochlorous acid oxygenated by myeloperoxidase modifies adjacent tryptophan and glycine residues in catalytic domain of matrix metalloproteinase-7 (Matrilysin). J Biol Chem 278:28403-28409, 2003.

Fu X, Kao J, Bergt C, Kassim SY, Huq NP, d'Avignon A, Parks WC, Mecham RP, Heinecke JW: Oxidative cross-linking of tryptophan to glycine restrains matrix metalloproteinase activity. J Biol Chem 279:6209-6212, 2004.

Bergt C, Fu X, Huq, NP, Kao J, Heinecke JW: Lysine residues direct the chlorination of tyrosines in YXXK motifs of apolipoprotein A-I when hypochlorous acid oxidizes high density lipoprotein. J Biol Chem 279:7856-7866, 2004.

Bergt C, Pennathur S, Fu X, Byun J, O’Brien K, McDonald TO, Singh P, Anantharamaiah GM, Chait A, Brunzell J, Geary RL, Oram JF, Heinecke JW: The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport. Proc Natl Acad Sci USA 101:13032-7, 2004.

Shao B, Bergt C, Fu X, Green P, Voss JC, Oda MN, Oram JF, Heinecke JW: Tyrosine 192 in apolipoprotein A-I is the major site of nitration and chlorination by myeloperoxidase, but only chlorination markedly impairs ABCA1-dependent cholesterol transport. J Biol Chem. 280(7):5983-93, 2005

Shao B, Belaaouaj A, Verlinde CL, Fu X, Heinecke JW. Methionine sulfoxide and proteolytic cleavage contribute to the inactivation of cathepsin G by hypochlorous acid: An oxidative mechanism for regulation of serine proteinases by myeloperoxidase. J. Biol Chem. 280(32) 29311-21, 2005.

Kassim SY, Fu X, Liles WC, Shapiro SD, Parks WC, Heinecke JW: NADPH Oxidase Restrains the Matrix Metalloproteinase Activity of Macrophages. J. Biol. Chem. 280(34): 30201-5, 2005.

Shao B, Fu X, Mecdonald TO, Green PS, Uchida K, O’Brien KD, Oram JF, Heinecke JW: Acrolein Impairs ABCA1-dependent Cholesterol Export from Cells through Site-Specific Modification of Apolipoprotein A-I. J. Biol. Chem. 280(43):36386-96, 2005.

Shao B, Oda MN, Bergt C, Fu X, Green PS, Brot N, Oram JF, Heinecke JW. Myeloperoxidase Impairs Abca1-Dependent Cholesterol Efflux Through Methionine Oxidation and Site-specific Tyrosine Chlorination of Apolipoprotein A-I. J. Biol. Chem. 281(14):9001-4, 2006.

Fu X, Wang Y, Kao J, Irwin A,d’Avignon A, Mecham RP, Parks WC, Heinecke JW: Specific Sequence Motifs Direct the Oxygenation and Chlorination of Tryptophan by Myeloperoxidase. Biochemistry 459(12), 3961-71, 2006

Wang Y, Rosen H, Madtes DK, Shao B, Martin TR, Heinecke JW, Fu X: Myeloperoxidase inactivates TIMP-1 by oxidizing its N-terminal cysteine residue: An oxidative mechanism for regulating proteolysis during inflammation. J. Biol. Chem. 282(44):31826-34, 2007

Fu X, Parks WC, Heinecke JW: Activation and silencing of matrix metalloproteinases. Semin Cell Dev Biol 19(1):2-13, 2008.

Fu X, Gharib SA, Green PS, Aitken ML, Frazer DA, Park DR, Vaisar T, Heinecke JW: Spectral Index for Assessment of Differential Protein Expression in Shotgun Proteomics. J. Proteome Res. 7(3) 845-854, 2008.