Neil C. Josephson Laboratory Publications

  1. Josephson NC, Sabo KM, Abkowitz JL: Transduction of feline hematopoietic cells by oncoretroviral vectors pseudotyped with the subgroup A feline leukemia virus (FeLV-A). Molecular Therapy 2000; 2(1): 56-62. PMID21300978
  2. Vassilopoulos G, Trobridge G, Josephson NC, Russell DW: Gene transfer into murine hematopoietic stem cells with helper-free foamy virus vectors. Blood 2001; 98(3): 604-609. PMID11468157
  3. Josephson NC, Vassilopoulos G, Trobridge GD, Priestley GV, Papayannopoulou T, Wood BL, Russell DW: Transduction of human NOD/SCID-repopulating cells with both lymphoid and myeloid potential by foamy virus vectors. Proceedings of the National Academy of Sciences 2002; 99(12): 8295-8300. PMID12060773
  4. Trobridge G, Josephson NC, Vassilopoulos G, Mac J, Russell DW: Improved foamy virus vectors with minimal viral sequences. Molecular Therapy 2002; 6(3):321-8. PMID12231167
  5. Josephson NC, Trobridge G, Russell DW: Transduction of long-term and mobilized peripheral blood-derived NOD/SCID repopulating cells by foamy virus vectors. Human Gene Therapy 2004; 15(1):87-92. PMID14965380
  6. Lanutti BJ, Epp A, Roy J, Chen J, Josephson NC: Incomplete restoration of Mpl expression in the mpl-/- mouse produces paradoxical thrombocytosis and partial correction of the stem cell repopulating defect. Blood 2009; 113(8):1778-85. PMID18796624
  7. Su RJ, Epp A, Latchman Y, Bolgiano D, Pipe SW, Josephson NC: Suppression of FVIII inhibitor formation in hemophilic mice by delivery of transgene modified apoptotic fibroblasts. Molecular Therapy 2010; 18(1): 214-22. PMID19755963
  8. Konkle BA, Josephson NC, Nakaya Fletcher SM, Thompson AR: Hemophilia A (September 2011) in: GeneReviews at GeneTests: Medical Genetics Information Resource [database online]. Copyright, University of Washington, Seattle, 1997-2010. Available at http://www.genetests.org.
  9. Konkle BA, Josephson NC, Nakaya Fletcher SM, Thompson AR: Hemophilia B (September 2011) in: GeneReviews at GeneTests: Medical Genetics Information Resource [database online]. Copyright, University of Washington, Seattle, 1997-2010. Available at http://www.genetests.org.
  10. Su RJ, Epp A, Feng J, Roy J, Latchman Y, Wu X, Bolgiano D, Josephson NC: Suppression of the Immune Response to FVIII in Hemophilia A Mice by Transgene Modified Tolerogenic Dendritic Cells. Molecular Therapy 19(10):1896-904, 2011. PMID21772255
  11. Ragni MV, Fogarty PJ, Josephson NC, Neff AT, Raffini LJ, Kessler CM: Survey of current prophylaxis practices and bleeding characteristics of children with severe haemophilia A in US haemophilia treatment centres. Haemophilia 2012; 18(1): 63-68. PMID21539695
  12. Shapiro AD, Ragni MV, Valentino LA, Key NS, Josephson NC, Powell JS, Cheng G, Thompson AR, Goyal J, Tubridy K, Peters RT, Dumont JA, Euwart D, Li L, Hallen B, Gozzi P, Bitonti AJ, Jiang H, Luk A, and Pierce GF: Recombinant factor IX-Fc fusion protein (rFIXFc) demonstrates safety and prolonged activity in a phase 1/2a study in hemophilia B patients. Blood Epub Nov 22, 2011. PMID22110246
  13. Nance D, Josephson NC, Paulyson-Nunez K, James AH.: Factor X deficiency and pregnancy: preconception counselling and therapeutic options. Haemophilia Epub Dec 12, 2011. PMID22151249
  14. Powell JS, Josephson NC, Quon D, Ragni MV, Cheng G, Li E, Jiang H, Li L, Dumont JA, Goyal J, Zhang X, Sommer J, McCue J, Barbetti M, Luk A, Pierce GF: Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients. Blood Epub Jan 5, 2012. PMID22223821